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Combining sotalol with beta-blockers such as atenolol tenormin , propranolol inderal , metoprolol lopressor , or calcium channel blockers such as verapamil calan, isoptin, verelan, covera-hs or diltiazem cardizem, dilacor, tiazac , may excessively slow heart rate or cause a block in the conduction of electrical impulses through the heart.
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Before taking diltiazemtell your doctor if you have kidney diseaseliver diseaseor congestive heart failure.
Ask your doctor if you have any questions about why these medicines have been prescribed for you.
These medicines belong to a group of medicines called calcium channel blockers or calcium antagonistsThey work by opening up blood vesselswhich lowers blood pressure and lets more blood and oxygen reach the heartThey do not change the amount of calcium in your blood or bones.
Coadministration of rifampin with diltiazem lowered the diltiazem plasma concentrations to undetectable levelsCoadministration of diltiazem with rifampin or any known CYP3A4 inducer should be avoided when possibleand alternative therapy considered.
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