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The use of angiotensin-converting enzyme inhibitors to control hypertension in patients on azathioprine has been reported to induce anemia and severe leukopenia.

In generalstarting dosage is from 1 to 3 mg/kg bodyweight/dayand should be adjustedwithin these limitsdepending on the clinical responsewhich may not be evident for weeks or monthsand haematological tolerance.

IMURAN should not be given to patients who have shown hypersensitivity to the drugIMURAN should not be used for treating rheumatoid arthritis in pregnant womenPatients with rheumatoid arthritis previously treated with alkylating agentscyclophosphamidechlorambucilmelphalanor othersmay have a prohibitive risk of malignancy if treated with IMURAN.

Imuran is an immune system-suppressing drugThat means that it can theoretically halt the attack of the immune system on your nerves if you have multiple sclerosisThe drug can be used to slow the progression of MS in people who are not responding well to other treatments.

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imuran 150 mg day pred 4mg every other day for 1 week then decrease by 1 mg week until on zero.

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