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Store at room temperature away from light and moistureDo not store in the bathroomKeep all medications away from children and pets.

NURSING MOTHERS In mothers treated with oral LIORESALbaclofen USPin therapeutic dosesthe active substance passes into the milkIt is not known whether detectable levels of drug are present in milk of nursing mothers receiving LIORESAL INTRATHECALAs a general rulenursing should be undertaken while a patient is receiving LIORESAL INTRATHECAL only if the potential benefit justifies the potential risks to the infant.

Symptoms of LIORESAL INTRATHECAL OverdoseDrowsinesslightheadednessdizzinesssomnolencerespiratory depressionhypothermiaseizuresrostral progression of hypotonia and loss of consciousness progressing to coma of up to 72 hrdurationIn most cases reportedcoma was reversible without sequelae after drug was discontinuedSymptoms of LIORESAL INTRATHECAL overdose were reported in a sensitive adult patient after receiving a 25 mcg intrathecal bolus.

Special attention must be given to recognizing the signs and symptoms of overdosageespecially during the initial screening and dose-titration phase of treatmentbut also during re-introduction of LIORESAL INTRATHECAL after a period of interruption in therapy.

A dose-related increase in incidence of ovarian cysts and a less marked increase in enlarged and/or hemorrhagic adrenal glands was observed in female rats treated chronically with Lioresal.

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drinking alcohol while taking this medication is not recommended, as it may increase the severity of certain side effects associated with lioresal.

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