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Taking synthroid over long periods of time may cause bone loss, which can lead to osteoporosis.

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Signs of an allergic reactionlike rashhivesitchingredswollenblisteredor peeling skin with or without feverwheezingtightness in the chest or throattrouble breathingswallowingor talkingunusual hoarsenessor swelling of the mouthfacelipstongueor throatChest pain or pressure or a fast heartbeatA heartbeat that does not feel normalShortness of breatha big weight gainor swelling in the arms or legsLump on your neckHeadacheFeeling more or less hungryA change in weight without tryingLoose stoolsdiarrheaStomach crampsThrowing upFeeling irritableFeeling nervous and excitableShakinessNot able to sleepBothered by heatSweating a lotFeverLeg crampsMuscle weaknessPeriodmenstrualchanges.

Store at room temperatureProtect from lightStore in a dry placeDo not store in a bathroomKeep all drugs in a safe placeKeep all drugs out of the reach of children and petsThrow away unused or expired drugsDo not flush down a toilet or pour down a drain unless you are told to do soCheck with your pharmacist if you have questions about the best way to throw out drugsThere may be drug take-back programs in your area.

Many drugs affect thyroid hormone pharmacokinetics and metabolisme.gabsorptionsynthesissecretioncatabolismprotein bindingand target tissue responseand may alter the therapeutic response to SYNTHROIDIn additionthyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugsA listing of drug-thyroidal axis interactions is contained in Table 2.

Many drugs affect thyroid hormone pharmacokinetics and metabolisme.gabsorptionsynthesissecretioncatabolismprotein bindingand target tissue responseand may alter the therapeutic response to SYNTHROIDIn additionthyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugsA listing of drug-thyroidal axis interactions is contained in Table 2.

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these medications include bile-acid sequestrant medications colestipol, welchol, questran , diazepam, hormone replacement therapies, thyroid medications synthroid, levothyroxine, levothroid and coumadin warfarin .

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